AMYLYX PHARMACEUTICALS INC (AMLX): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in AMLX · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
21
13F filers
Aggregate Value
$116.4M
Across holders
Last Price
$38.15
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity12 increased8 reduced3 exited
Full exits: Verition Fund Management LLC, Point72 Asset Management, L.P., Squarepoint Ops LLC
Institutional Holders of AMLX
21 holders
ManagerTypeSharesMarket Value% of Total% of PortfolioActionQoQ ChangeQuarter
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
Hedge Fund1.90M$34.1M29.3%0.0%Reduced$-29.8MQ2 2026
Woodline Partners LP
CIK 0001784547
Hedge Fund846K$15.2M13.1%0.0%Added+$11KQ2 2026
BALYASNY ASSET MANAGEMENT LLC
CIK 0001218710
Hedge Fund685K$12.3M10.6%0.0%Reduced$-7.6MQ2 2026
Qube Research & Technologies Ltd
CIK 0001729829
Hedge Fund681K$12.2M10.5%0.0%Reduced$-374KQ2 2026
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
Hedge Fund593K$10.7M9.2%0.0%Added+$7.7MQ2 2026
Tetragon Partners GP Ltd
CIK 0001515070
Hedge Fund298K$5.4M4.6%0.8%Reduced$-358KQ2 2026
JUPITER ASSET MANAGEMENT LTD
CIK 0001215838
Hedge Fund275K$4.9M4.2%0.0%Reduced$-5.7MQ2 2026
Walleye Capital LLC
CIK 0001758720
Hedge Fund187K$3.4M2.9%0.0%Added+$3.3MQ2 2026
ORBIMED ADVISORS LLC
CIK 0001055951
Hedge Fund183K$3.3M2.8%0.1%AddedQ2 2026
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund179K$3.2M2.8%0.0%Reduced+$2.7MQ2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Reduced
Hedge Fund
$34.1M· 29.3% of total· 0.0% port· 1.90M sh· $-29.8M QoQ· Q2 2026
Woodline Partners LPAdded
Hedge Fund
$15.2M· 13.1% of total· 0.0% port· 846K sh· +$11K QoQ· Q2 2026
BALYASNY ASSET MANAGEMENT LLCReduced
Hedge Fund
$12.3M· 10.6% of total· 0.0% port· 685K sh· $-7.6M QoQ· Q2 2026
Qube Research & Technologies LtdReduced
Hedge Fund
$12.2M· 10.5% of total· 0.0% port· 681K sh· $-374K QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPAdded
Hedge Fund
$10.7M· 9.2% of total· 0.0% port· 593K sh· +$7.7M QoQ· Q2 2026
Tetragon Partners GP LtdReduced
Hedge Fund
$5.4M· 4.6% of total· 0.8% port· 298K sh· $-358K QoQ· Q2 2026
JUPITER ASSET MANAGEMENT LTDReduced
Hedge Fund
$4.9M· 4.2% of total· 0.0% port· 275K sh· $-5.7M QoQ· Q2 2026
Walleye Capital LLCAdded
Hedge Fund
$3.4M· 2.9% of total· 0.0% port· 187K sh· +$3.3M QoQ· Q2 2026
ORBIMED ADVISORS LLCAdded
Hedge Fund
$3.3M· 2.8% of total· 0.1% port· 183K sh· QoQ· Q2 2026
CITADEL ADVISORS LLCReduced
Hedge Fund
$3.2M· 2.8% of total· 0.0% port· 179K sh· +$2.7M QoQ· Q2 2026
SHAW D E & CO INCAdded
Hedge Fund
$3.1M· 2.7% of total· 0.0% port· 174K sh· +$1.9M QoQ· Q2 2026
Alpha Wave Global, LPAdded
Hedge Fund
$2.8M· 2.4% of total· 0.0% port· 155K sh· +$235K QoQ· Q2 2026
Lighthouse Investment Partners, LLCAdded
Hedge Fund
$2.2M· 1.9% of total· 0.1% port· 123K sh· QoQ· Q2 2026
Schonfeld Strategic Advisors LLCReduced
Hedge Fund
$1.2M· 1.0% of total· 0.0% port· 67K sh· $-197K QoQ· Q2 2026
Hudson Bay Capital Management LPAdded
Hedge Fund
$898K· 0.8% of total· 0.0% port· 50K sh· QoQ· Q2 2026
TUDOR INVESTMENT CORP ET ALAdded
Hedge Fund
$636K· 0.5% of total· 0.0% port· 35K sh· +$73K QoQ· Q2 2026
AQR CAPITAL MANAGEMENT LLCReduced
Hedge Fund
$374K· 0.3% of total· 0.0% port· 21K sh· +$372K QoQ· Q2 2026
Magnetar Financial LLCAdded
Hedge Fund
$211K· 0.2% of total· 0.0% port· 12K sh· QoQ· Q2 2026
Brevan Howard Capital Management LPAdded
Hedge Fund
$209K· 0.2% of total· 0.0% port· 12K sh· QoQ· Q2 2026
Fulcrum Asset Management LLPAdded
Hedge Fund
$82K· 0.1% of total· 0.0% port· 4K sh· QoQ· Q2 2026
Rockefeller Capital Management L.P.Unchanged
Hedge Fund
$23K· 0.0% of total· 0.0% port· 1K sh· $-14K QoQ· Q2 2026
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