Stock Ownership/SEPN

SEPTERNA INC (SEPN): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in SEPN · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
16
13F filers
Aggregate Value
$76.4M
Across holders
Last Price
$40.52
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity14 increased2 reduced3 exited
Full exits: Verition Fund Management LLC, ADAGE CAPITAL PARTNERS GP, L.L.C., MARSHALL WACE, LLP
Institutional Holders of SEPN
↗
16 holders
Manager⇅Type⇅Shares⇅Market Value▼% of Total⇅% of Portfolio⇅Action⇅QoQ Change⇅Quarter⇅
PRIMECAP MANAGEMENT CO/CA/
CIK 0000763212
Institutional Manager1.17M$39.1M51.2%0.0%Added+$4.0MQ2 2026
BALYASNY ASSET MANAGEMENT LLC
CIK 0001218710
Hedge Fund350K$11.7M15.4%0.0%Added+$3.8MQ2 2026
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
Hedge Fund221K$7.4M9.7%0.0%Added+$4.9MQ2 2026
Woodline Partners LP
CIK 0001784547
Hedge Fund186K$6.2M8.1%0.0%Added—Q2 2026
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP
CIK 0001164508
Hedge Fund75K$2.5M3.3%0.0%Added—Q2 2026
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
Hedge Fund51K$1.7M2.2%0.0%Reduced$-2.5MQ2 2026
SHAW D E & CO INC
CIK 0001009207
Hedge Fund46K$1.6M2.0%0.0%Added—Q2 2026
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
Hedge Fund41K$1.4M1.8%0.0%Added+$125KQ2 2026
Brevan Howard Capital Management LP
CIK 0001512857
Hedge Fund29K$986K1.3%0.0%Added—Q2 2026
TUDOR INVESTMENT CORP ET AL
CIK 0000923093
Hedge Fund29K$970K1.3%0.0%Added—Q2 2026
PRIMECAP MANAGEMENT CO/CA/Added
Institutional Manager
$39.1M· 51.2% of total· 0.0% port· 1.17M sh· +$4.0M QoQ· Q2 2026
BALYASNY ASSET MANAGEMENT LLCAdded
Hedge Fund
$11.7M· 15.4% of total· 0.0% port· 350K sh· +$3.8M QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPAdded
Hedge Fund
$7.4M· 9.7% of total· 0.0% port· 221K sh· +$4.9M QoQ· Q2 2026
Woodline Partners LPAdded
Hedge Fund
$6.2M· 8.1% of total· 0.0% port· 186K sh· — QoQ· Q2 2026
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPAdded
Hedge Fund
$2.5M· 3.3% of total· 0.0% port· 75K sh· — QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCReduced
Hedge Fund
$1.7M· 2.2% of total· 0.0% port· 51K sh· $-2.5M QoQ· Q2 2026
SHAW D E & CO INCAdded
Hedge Fund
$1.6M· 2.0% of total· 0.0% port· 46K sh· — QoQ· Q2 2026
RENAISSANCE TECHNOLOGIES LLCAdded
Hedge Fund
$1.4M· 1.8% of total· 0.0% port· 41K sh· +$125K QoQ· Q2 2026
Brevan Howard Capital Management LPAdded
Hedge Fund
$986K· 1.3% of total· 0.0% port· 29K sh· — QoQ· Q2 2026
TUDOR INVESTMENT CORP ET ALAdded
Hedge Fund
$970K· 1.3% of total· 0.0% port· 29K sh· — QoQ· Q2 2026
Squarepoint Ops LLCAdded
Hedge Fund
$711K· 0.9% of total· 0.0% port· 21K sh· +$105K QoQ· Q2 2026
FRED ALGER MANAGEMENT, LLCAdded
Hedge Fund
$702K· 0.9% of total· 0.0% port· 21K sh· — QoQ· Q2 2026
AQR CAPITAL MANAGEMENT LLCAdded
Hedge Fund
$516K· 0.7% of total· 0.0% port· 15K sh· +$505K QoQ· Q2 2026
Man Group plcReduced
Hedge Fund
$384K· 0.5% of total· 0.0% port· 11K sh· $-13K QoQ· Q2 2026
Gotham Asset Management, LLCAdded
Hedge Fund
$312K· 0.4% of total· 0.0% port· 9K sh· — QoQ· Q2 2026
CITADEL ADVISORS LLCAdded
Hedge Fund
$213K· 0.3% of total· 0.0% port· 6K sh· — QoQ· Q2 2026
1–10 of 16
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