SPERO THERAPEUTICS INC (SPRO): Ownership & Insider Activity
Hedge funds and institutional managers reporting a position in SPRO · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.
Reported Holders
6
13F filers
Aggregate Value
$4.0M
Across holders
Last Price
$1.22
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity4 increased2 reduced4 exited
| Manager⇅ | Type⇅ | Shares⇅ | Market Value▼ | % of Total⇅ | % of Portfolio⇅ | Action⇅ | QoQ Change⇅ | Quarter⇅ |
|---|---|---|---|---|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC CIK 0001037389 | Hedge Fund | 948K | $2.1M | 52.6% | 0.0% | Reduced | $-533K | Q2 2026 |
| TWO SIGMA INVESTMENTS, LP CIK 0001179392 | Hedge Fund | 383K | $846K | 21.3% | 0.0% | Reduced | $-1.1M | Q2 2026 |
| ARROWSTREET CAPITAL, LIMITED PARTNERSHIP CIK 0001164508 | Hedge Fund | 333K | $736K | 18.5% | 0.0% | Added | — | Q2 2026 |
| Point72 Asset Management, L.P. CIK 0001603466 | Hedge Fund | 104K | $231K | 5.8% | 0.0% | Added | +$99K | Q2 2026 |
| MILLENNIUM MANAGEMENT LLC CIK 0001273087 | Hedge Fund | 19K | $43K | 1.1% | 0.0% | Added | — | Q2 2026 |
| Qube Research & Technologies Ltd CIK 0001729829 | Hedge Fund | 14K | $30K | 0.8% | 0.0% | Added | — | Q2 2026 |
Reduced
Hedge Fund
$2.1M· 52.6% of total· 0.0% port· 948K sh· $-533K QoQ· Q2 2026
Reduced
Hedge Fund
$846K· 21.3% of total· 0.0% port· 383K sh· $-1.1M QoQ· Q2 2026
Added
Hedge Fund
$736K· 18.5% of total· 0.0% port· 333K sh· — QoQ· Q2 2026
Added
Hedge Fund
$231K· 5.8% of total· 0.0% port· 104K sh· +$99K QoQ· Q2 2026
Added
Hedge Fund
$43K· 1.1% of total· 0.0% port· 19K sh· — QoQ· Q2 2026
Added
Hedge Fund
$30K· 0.8% of total· 0.0% port· 14K sh· — QoQ· Q2 2026
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