BAKER BROS. ADVISORS LP
Hedge FundCIKLocation
Long U.S. equity positions disclosed to the SEC on Form 13F-HR.
Latest filingQ2 2026Quarter ended30 Jun 2026Filed14 Aug 2026
Firm profile · Form ADV
SEC adviser registrationBAKER BROS. ADVISORS LP, established in January 2000, is an investment adviser that provides discretionary investment advisory services to private investment funds. The firm's investment strategy involves investing in public and private securities and related assets of life sciences and health care companies, as well as cash management investments. These investments can include equity securities, corporate debt, options, ETFs, money market funds, and royalties, with a focus on public securities but also including private companies and intellectual property.Summarised from the firm’s Form ADV Part 2A brochure.
Portfolio Turnover
3%
Of book traded, QoQ
Positions
84
Long U.S. equities
Top 10 Concentration
73%
Of reported value
QoQ Change
$2.5B
Value change
Assets under management
Form ADV RAUM · client mix · 13F over timeRegulatory AUM
$28.1B
Form ADV, as of Mar 2026
● 100% discretionary ($28.1B)
By client type
13F AUM over time
$20.0B
Q2 ’26 · 13F AUM
▲ 110%
42 quarters
Loading position history…
| Security⇅ | Shares⇅ | Market Value▼ | Est. Cost⇅ | Last Px⇅ | Est. Return⇅ | % Portfolio⇅ | Δ Shares⇅ | Action⇅ |
|---|---|---|---|---|---|---|---|---|
| 30.76MSH | $3.5B | ~$113.36 | $126.75 | ▲11.8% | 17.5% | ▲ 0.1% | Added | |
| 8.80MSH | $2.5B | ~$284.97 | $358.26 | ▲25.7% | 12.6% | ▲ 0.0% | Added | |
| 11.44MSH | $2.1B | ~$187.28 | $210.02 | ▲12.1% | 10.7% | ▲ 19.8% | Added | |
| 2.14MSH | $1.2B | ~$536.95 | $541.08 | ▲0.8% | 5.8% | ▲ 0.1% | Added | |
| 42.91MSH | $1.1B | ~$25.30 | $28.02 | ▲10.8% | 5.4% | ▲ 0.0% | Added | |
| 8.66MSH | $992.7M | ~$114.67 | $117.39 | ▲2.4% | 5.0% | — | Unchanged | |
| 8.80MSH | $937.8M | ~$106.62 | $126.29 | ▲18.4% | 4.7% | ▲ 18.5% | Added | |
| 7.92MSH | $828.2M | ~$104.62 | $95.70 | ▼8.5% | 4.2% | — | Unchanged | |
| 19.92MSH | $776.1M | ~$38.96 | $35.36 | ▼9.2% | 3.9% | — | Unchanged | |
| 5.60MSH | $622.3M | ~$111.03 | $102.74 | ▼7.5% | 3.1% | — | Unchanged |
INCYAdded
$3.5B· 17.5%· 30.76M SH· ▲ 0.1%· cost $113.36· last $126.75· ▲11.8%
ONCAdded
$2.5B· 12.6%· 8.80M SH· ▲ 0.0%· cost $284.97· last $358.26· ▲25.7%
RVMDAdded
$2.1B· 10.7%· 11.44M SH· ▲ 19.8%· cost $187.28· last $210.02· ▲12.1%
MDGLAdded
$1.2B· 5.8%· 2.14M SH· ▲ 0.1%· cost $536.95· last $541.08· ▲0.8%
ACADAdded
$1.1B· 5.4%· 42.91M SH· ▲ 0.0%· cost $25.30· last $28.02· ▲10.8%
KYMRUnchanged
$992.7M· 5.0%· 8.66M SH· —· cost $114.67· last $117.39· ▲2.4%
INSMAdded
$937.8M· 4.7%· 8.80M SH· ▲ 18.5%· cost $106.62· last $126.29· ▲18.4%
CELCUnchanged
$828.2M· 4.2%· 7.92M SH· —· cost $104.62· last $95.70· ▼8.5%
KODUnchanged
$776.1M· 3.9%· 19.92M SH· —· cost $38.96· last $35.36· ▼9.2%
RYTMUnchanged
$622.3M· 3.1%· 5.60M SH· —· cost $111.03· last $102.74· ▼7.5%
1–10 of 84
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Sector Breakdown
Q2 2026Health Care94.2% · $18.8B
Unclassified5.8% · $1.2B