AXSOME THERAPEUTICS INC. (AXSM): Ownership & Insider Activity
Hedge funds and institutional managers reporting a position in AXSM · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.
Reported Holders
29
13F filers
Aggregate Value
$1.2B
Across holders
Last Price
$205.40
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity20 increased8 reduced3 exited
| Manager⇅ | Type⇅ | Shares⇅ | Market Value▼ | % of Total⇅ | % of Portfolio⇅ | Action⇅ | QoQ Change⇅ | Quarter⇅ |
|---|---|---|---|---|---|---|---|---|
| TWO SIGMA INVESTMENTS, LP CIK 0001179392 | Hedge Fund | 669K | $163.9M | 13.4% | 0.1% | Added | +$163.0M | Q2 2026 |
| SHAW D E & CO INC CIK 0001009207 | Hedge Fund | 605K | $148.0M | 12.1% | 0.1% | Added | $-82.2M | Q2 2026 |
| MILLENNIUM MANAGEMENT LLC CIK 0001273087 | Hedge Fund | 556K | $136.1M | 11.1% | 0.0% | Added | +$128.7M | Q2 2026 |
| Qube Research & Technologies Ltd CIK 0001729829 | Hedge Fund | 426K | $104.4M | 8.5% | 0.1% | Added | +$22.3M | Q2 2026 |
| Point72 Asset Management, L.P. CIK 0001603466 | Hedge Fund | 417K | $102.0M | 8.3% | 0.1% | Reduced | $-2.0M | Q2 2026 |
| RENAISSANCE TECHNOLOGIES LLC CIK 0001037389 | Hedge Fund | 262K | $64.1M | 5.2% | 0.1% | Added | +$23.9M | Q2 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 0001165408 | Hedge Fund | 259K | $63.4M | 5.2% | 0.1% | Reduced | $-117.1M | Q2 2026 |
| CITADEL ADVISORS LLC CIK 0001423053 | Hedge Fund | 256K | $62.6M | 5.1% | 0.0% | Reduced | +$62.6M | Q2 2026 |
| Clearbridge Investments, LLC CIK 0001348883 | Hedge Fund | 246K | $60.1M | 4.9% | 0.0% | Added | +$49.1M | Q2 2026 |
| MARSHALL WACE, LLP CIK 0001318757 | Hedge Fund | 223K | $54.7M | 4.5% | 0.0% | Added | $-11.6M | Q2 2026 |
Added
Hedge Fund
$163.9M· 13.4% of total· 0.1% port· 669K sh· +$163.0M QoQ· Q2 2026
Added
Hedge Fund
$148.0M· 12.1% of total· 0.1% port· 605K sh· $-82.2M QoQ· Q2 2026
Added
Hedge Fund
$136.1M· 11.1% of total· 0.0% port· 556K sh· +$128.7M QoQ· Q2 2026
Added
Hedge Fund
$104.4M· 8.5% of total· 0.1% port· 426K sh· +$22.3M QoQ· Q2 2026
Reduced
Hedge Fund
$102.0M· 8.3% of total· 0.1% port· 417K sh· $-2.0M QoQ· Q2 2026
Added
Hedge Fund
$64.1M· 5.2% of total· 0.1% port· 262K sh· +$23.9M QoQ· Q2 2026
Reduced
Hedge Fund
$63.4M· 5.2% of total· 0.1% port· 259K sh· $-117.1M QoQ· Q2 2026
Reduced
Hedge Fund
$62.6M· 5.1% of total· 0.0% port· 256K sh· +$62.6M QoQ· Q2 2026
Added
Hedge Fund
$60.1M· 4.9% of total· 0.0% port· 246K sh· +$49.1M QoQ· Q2 2026
Added
Hedge Fund
$54.7M· 4.5% of total· 0.0% port· 223K sh· $-11.6M QoQ· Q2 2026
Unchanged
Hedge Fund
$39.7M· 3.2% of total· 0.1% port· 162K sh· +$0 QoQ· Q2 2026
Added
Hedge Fund
$37.8M· 3.1% of total· 0.0% port· 155K sh· +$37.5M QoQ· Q2 2026
Added
Hedge Fund
$33.1M· 2.7% of total· 0.0% port· 135K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$28.8M· 2.4% of total· 0.5% port· 118K sh· $-23.6M QoQ· Q2 2026
Added
Hedge Fund
$27.9M· 2.3% of total· 0.0% port· 114K sh· +$27.9M QoQ· Q2 2026
Reduced
Hedge Fund
$20.2M· 1.7% of total· 0.0% port· 83K sh· $-14.6M QoQ· Q2 2026
Added
Hedge Fund
$18.7M· 1.5% of total· 0.0% port· 76K sh· — QoQ· Q2 2026
Added
Hedge Fund
$14.2M· 1.2% of total· 0.1% port· 58K sh· +$310K QoQ· Q2 2026
Added
Hedge Fund
$10.5M· 0.9% of total· 0.0% port· 43K sh· +$3.9M QoQ· Q2 2026
Added
Hedge Fund
$8.7M· 0.7% of total· 0.0% port· 36K sh· — QoQ· Q2 2026
Added
Hedge Fund
$7.8M· 0.6% of total· 0.1% port· 32K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$5.5M· 0.5% of total· 0.0% port· 23K sh· $-8.3M QoQ· Q2 2026
Added
Hedge Fund
$4.6M· 0.4% of total· 0.0% port· 19K sh· — QoQ· Q2 2026
Added
Hedge Fund
$2.6M· 0.2% of total· 0.1% port· 10K sh· +$1.8M QoQ· Q2 2026
Added
Hedge Fund
$1.5M· 0.1% of total· 0.0% port· 6K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$1.1M· 0.1% of total· 0.0% port· 4K sh· $-5K QoQ· Q2 2026
Added
Hedge Fund
$920K· 0.1% of total· 0.0% port· 4K sh· $-1.4M QoQ· Q2 2026
Reduced
Hedge Fund
$420K· 0.0% of total· 0.0% port· 2K sh· +$371K QoQ· Q2 2026
Added
Hedge Fund
$240K· 0.0% of total· 0.0% port· 980 sh· — QoQ· Q2 2026
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