Stock Ownership/DFTX

DEFINIUM THERAPEUTICS INC (DFTX): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in DFTX · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
22
13F filers
Aggregate Value
$543.8M
Across holders
Last Price
$43.27
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity13 increased9 reduced5 exited
Full exits: ExodusPoint Capital Management, LP, Verition Fund Management LLC, CAXTON ASSOCIATES LLP, Squarepoint Ops LLC, Magnetar Financial LLC
Institutional Holders of DFTX
↗
22 holders
Manager⇅Type⇅Shares⇅Market Value▼% of Total⇅% of Portfolio⇅Action⇅QoQ Change⇅Quarter⇅
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund1.69M$79.4M14.6%0.0%Added+$71.4MQ2 2026
MARSHALL WACE, LLP
CIK 0001318757
Hedge Fund1.30M$61.1M11.2%0.0%Added$-108.4MQ2 2026
Woodline Partners LP
CIK 0001784547
Hedge Fund1.00M$47.2M8.7%0.1%Added+$11.8MQ2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
Hedge Fund1.00M$47.0M8.7%0.1%Reduced$-7.1MQ2 2026
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
Hedge Fund922K$43.4M8.0%0.0%Reduced$-13.2MQ2 2026
BALYASNY ASSET MANAGEMENT LLC
CIK 0001218710
Hedge Fund898K$42.2M7.8%0.1%Reduced$-77.7MQ2 2026
Holocene Advisors, LP
CIK 0001700574
Hedge Fund797K$37.5M6.9%0.1%Reduced$-13.9MQ2 2026
Qube Research & Technologies Ltd
CIK 0001729829
Hedge Fund683K$32.1M5.9%0.0%Added+$12.1MQ2 2026
ArrowMark Colorado Holdings LLC
CIK 0001483859
Hedge Fund564K$26.5M4.9%1.1%Reduced$-48.5MQ2 2026
Point72 Asset Management, L.P.
CIK 0001603466
Hedge Fund484K$22.8M4.2%0.0%Added+$14.5MQ2 2026
CITADEL ADVISORS LLCAdded
Hedge Fund
$79.4M· 14.6% of total· 0.0% port· 1.69M sh· +$71.4M QoQ· Q2 2026
MARSHALL WACE, LLPAdded
Hedge Fund
$61.1M· 11.2% of total· 0.0% port· 1.30M sh· $-108.4M QoQ· Q2 2026
Woodline Partners LPAdded
Hedge Fund
$47.2M· 8.7% of total· 0.1% port· 1.00M sh· +$11.8M QoQ· Q2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Reduced
Hedge Fund
$47.0M· 8.7% of total· 0.1% port· 1.00M sh· $-7.1M QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPReduced
Hedge Fund
$43.4M· 8.0% of total· 0.0% port· 922K sh· $-13.2M QoQ· Q2 2026
BALYASNY ASSET MANAGEMENT LLCReduced
Hedge Fund
$42.2M· 7.8% of total· 0.1% port· 898K sh· $-77.7M QoQ· Q2 2026
Holocene Advisors, LPReduced
Hedge Fund
$37.5M· 6.9% of total· 0.1% port· 797K sh· $-13.9M QoQ· Q2 2026
Qube Research & Technologies LtdAdded
Hedge Fund
$32.1M· 5.9% of total· 0.0% port· 683K sh· +$12.1M QoQ· Q2 2026
ArrowMark Colorado Holdings LLCReduced
Hedge Fund
$26.5M· 4.9% of total· 1.1% port· 564K sh· $-48.5M QoQ· Q2 2026
Point72 Asset Management, L.P.Added
Hedge Fund
$22.8M· 4.2% of total· 0.0% port· 484K sh· +$14.5M QoQ· Q2 2026
ORBIMED ADVISORS LLCReduced
Hedge Fund
$17.2M· 3.2% of total· 0.3% port· 365K sh· $-20.6M QoQ· Q2 2026
Duquesne Family Office LLCAdded
Family Office
$16.8M· 3.1% of total· 0.3% port· 357K sh· — QoQ· Q2 2026
SHAW D E & CO INCAdded
Hedge Fund
$14.8M· 2.7% of total· 0.0% port· 315K sh· $-3.8M QoQ· Q2 2026
Tetragon Partners GP LtdAdded
Hedge Fund
$13.5M· 2.5% of total· 2.1% port· 287K sh· +$4.1M QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCReduced
Hedge Fund
$12.5M· 2.3% of total· 0.0% port· 266K sh· $-27.3M QoQ· Q2 2026
Brevan Howard Capital Management LPReduced
Hedge Fund
$7.4M· 1.4% of total· 0.1% port· 157K sh· $-12.5M QoQ· Q2 2026
AQR CAPITAL MANAGEMENT LLCAdded
Hedge Fund
$6.3M· 1.2% of total· 0.0% port· 134K sh· $-9.7M QoQ· Q2 2026
FRED ALGER MANAGEMENT, LLCAdded
Hedge Fund
$5.9M· 1.1% of total· 0.0% port· 125K sh· +$1.6M QoQ· Q2 2026
Schonfeld Strategic Advisors LLCAdded
Hedge Fund
$5.6M· 1.0% of total· 0.0% port· 120K sh· +$5.1M QoQ· Q2 2026
Rockefeller Capital Management L.P.Added
Hedge Fund
$3.3M· 0.6% of total· 0.0% port· 70K sh· +$701K QoQ· Q2 2026
Walleye Capital LLCReduced
Hedge Fund
$971K· 0.2% of total· 0.0% port· 21K sh· $-698K QoQ· Q2 2026
Gotham Asset Management, LLCAdded
Hedge Fund
$208K· 0.0% of total· 0.0% port· 4K sh· — QoQ· Q2 2026
1–10 of 22
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