Stock Ownership/KPTI

KARYOPHARM THERAPEUTICS INC (KPTI): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in KPTI · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
10
13F filers
Aggregate Value
$34.3M
Across holders
Last Price
$1.86
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity6 increased2 reduced3 exited
Full exits: BALYASNY ASSET MANAGEMENT LLC, Tetragon Partners GP Ltd, Rockefeller Capital Management L.P.
Institutional Holders of KPTI
↗
10 holders
Manager⇅Type⇅Shares⇅Market Value▼% of Total⇅% of Portfolio⇅Action⇅QoQ Change⇅Quarter⇅
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
Hedge Fund1.52M$14.9M43.3%0.0%Reduced$-2.8MQ2 2026
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
Hedge Fund695K$6.8M19.8%0.0%Added+$5.3MQ2 2026
Brevan Howard Capital Management LP
CIK 0001512857
Hedge Fund310K$3.0M8.8%0.0%Added+$952KQ2 2026
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
Hedge Fund306K$3.0M8.7%0.0%Reduced$-1.1MQ2 2026
Davidson Kempner Capital Management LP
CIK 0001595082
Hedge Fund300K$2.9M8.5%0.0%Unchanged+$0Q2 2026
MARSHALL WACE, LLP
CIK 0001318757
Hedge Fund128K$1.3M3.7%0.0%Unchanged$-502KQ2 2026
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
Hedge Fund108K$1.1M3.1%0.0%Added+$27KQ2 2026
Squarepoint Ops LLC
CIK 0001642575
Hedge Fund64K$623K1.8%0.0%Added—Q2 2026
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund52K$509K1.5%0.0%Added$-2.0MQ2 2026
ExodusPoint Capital Management, LP
CIK 0001736225
Hedge Fund27K$260K0.8%0.0%Added—Q2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Reduced
Hedge Fund
$14.9M· 43.3% of total· 0.0% port· 1.52M sh· $-2.8M QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPAdded
Hedge Fund
$6.8M· 19.8% of total· 0.0% port· 695K sh· +$5.3M QoQ· Q2 2026
Brevan Howard Capital Management LPAdded
Hedge Fund
$3.0M· 8.8% of total· 0.0% port· 310K sh· +$952K QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCReduced
Hedge Fund
$3.0M· 8.7% of total· 0.0% port· 306K sh· $-1.1M QoQ· Q2 2026
Davidson Kempner Capital Management LPUnchanged
Hedge Fund
$2.9M· 8.5% of total· 0.0% port· 300K sh· +$0 QoQ· Q2 2026
MARSHALL WACE, LLPUnchanged
Hedge Fund
$1.3M· 3.7% of total· 0.0% port· 128K sh· $-502K QoQ· Q2 2026
RENAISSANCE TECHNOLOGIES LLCAdded
Hedge Fund
$1.1M· 3.1% of total· 0.0% port· 108K sh· +$27K QoQ· Q2 2026
Squarepoint Ops LLCAdded
Hedge Fund
$623K· 1.8% of total· 0.0% port· 64K sh· — QoQ· Q2 2026
CITADEL ADVISORS LLCAdded
Hedge Fund
$509K· 1.5% of total· 0.0% port· 52K sh· $-2.0M QoQ· Q2 2026
ExodusPoint Capital Management, LPAdded
Hedge Fund
$260K· 0.8% of total· 0.0% port· 27K sh· — QoQ· Q2 2026
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