Stock Ownership/PRLD

PRELUDE THERAPEUTICS INC (PRLD): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in PRLD · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
11
13F filers
Aggregate Value
$144.1M
Across holders
Last Price
$6.47
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity7 increased3 reduced1 exited
Full exits: Point72 Asset Management, L.P.
Institutional Holders of PRLD
↗
11 holders
Manager⇅Type⇅Shares⇅Market Value▼% of Total⇅% of Portfolio⇅Action⇅QoQ Change⇅Quarter⇅
ORBIMED ADVISORS LLC
CIK 0001055951
Hedge Fund13.72M$73.2M50.8%1.4%Added+$15.0MQ2 2026
BAKER BROS. ADVISORS LP
CIK 0001263508
Hedge Fund10.12M$54.0M37.4%0.3%Unchanged+$0Q2 2026
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
Hedge Fund993K$5.3M3.7%0.0%Added+$372KQ2 2026
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
Hedge Fund845K$4.5M3.1%0.0%Added+$2.5MQ2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
Hedge Fund766K$4.1M2.8%0.0%Added—Q2 2026
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
Hedge Fund281K$1.5M1.0%0.0%Added+$32KQ2 2026
MARSHALL WACE, LLP
CIK 0001318757
Hedge Fund191K$1.0M0.7%0.0%Reduced$-812KQ2 2026
Squarepoint Ops LLC
CIK 0001642575
Hedge Fund60K$317K0.2%0.0%Added—Q2 2026
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund23K$120K0.1%0.0%Reduced$-1.2MQ2 2026
ExodusPoint Capital Management, LP
CIK 0001736225
Hedge Fund15K$82K0.1%0.0%Added—Q2 2026
ORBIMED ADVISORS LLCAdded
Hedge Fund
$73.2M· 50.8% of total· 1.4% port· 13.72M sh· +$15.0M QoQ· Q2 2026
BAKER BROS. ADVISORS LPUnchanged
Hedge Fund
$54.0M· 37.4% of total· 0.3% port· 10.12M sh· +$0 QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPAdded
Hedge Fund
$5.3M· 3.7% of total· 0.0% port· 993K sh· +$372K QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCAdded
Hedge Fund
$4.5M· 3.1% of total· 0.0% port· 845K sh· +$2.5M QoQ· Q2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Added
Hedge Fund
$4.1M· 2.8% of total· 0.0% port· 766K sh· — QoQ· Q2 2026
RENAISSANCE TECHNOLOGIES LLCAdded
Hedge Fund
$1.5M· 1.0% of total· 0.0% port· 281K sh· +$32K QoQ· Q2 2026
MARSHALL WACE, LLPReduced
Hedge Fund
$1.0M· 0.7% of total· 0.0% port· 191K sh· $-812K QoQ· Q2 2026
Squarepoint Ops LLCAdded
Hedge Fund
$317K· 0.2% of total· 0.0% port· 60K sh· — QoQ· Q2 2026
CITADEL ADVISORS LLCReduced
Hedge Fund
$120K· 0.1% of total· 0.0% port· 23K sh· $-1.2M QoQ· Q2 2026
ExodusPoint Capital Management, LPAdded
Hedge Fund
$82K· 0.1% of total· 0.0% port· 15K sh· — QoQ· Q2 2026
Qube Research & Technologies LtdReduced
Hedge Fund
$70K· 0.0% of total· 0.0% port· 13K sh· $-18K QoQ· Q2 2026
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