PROTAGONIST THERAPEUTICS INC (PTGX): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in PTGX · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
21
13F filers
Aggregate Value
$1.1B
Across holders
Last Price
$154.72
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity11 increased7 reduced3 exited
Full exits: Hudson Bay Capital Management LP, ADAGE CAPITAL PARTNERS GP, L.L.C., CITADEL ADVISORS LLC
Institutional Holders of PTGX
21 holders
ManagerTypeSharesMarket Value% of Total% of PortfolioActionQoQ ChangeQuarter
FARALLON CAPITAL MANAGEMENT LLC
CIK 0000909661
Hedge Fund6.35M$778.2M68.5%3.6%Unchanged+$0Q2 2026
Woodline Partners LP
CIK 0001784547
Hedge Fund1.41M$173.3M15.2%0.5%Unchanged+$0Q2 2026
Clearbridge Investments, LLC
CIK 0001348883
Hedge Fund725K$88.9M7.8%0.1%Added+$12.7MQ2 2026
Duquesne Family Office LLC
CIK 0001536411
Family Office209K$25.6M2.3%0.5%Added+$6.0MQ2 2026
Fisher Asset Management, LLC
CIK 0000850529
Institutional Manager171K$20.9M1.8%0.0%Reduced$-423KQ2 2026
MARSHALL WACE, LLP
CIK 0001318757
Hedge Fund109K$13.4M1.2%0.0%Reduced$-133.3MQ2 2026
AXIOM INVESTORS LLC /DE
CIK 0001109147
Hedge Fund82K$10.0M0.9%0.1%Reduced$-465KQ2 2026
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP
CIK 0001164508
Hedge Fund45K$5.5M0.5%0.0%AddedQ2 2026
ORBIMED ADVISORS LLC
CIK 0001055951
Hedge Fund42K$5.2M0.5%0.1%Unchanged+$0Q2 2026
Schonfeld Strategic Advisors LLC
CIK 0001665241
Hedge Fund28K$3.4M0.3%0.0%AddedQ2 2026
FARALLON CAPITAL MANAGEMENT LLCUnchanged
Hedge Fund
$778.2M· 68.5% of total· 3.6% port· 6.35M sh· +$0 QoQ· Q2 2026
Woodline Partners LPUnchanged
Hedge Fund
$173.3M· 15.2% of total· 0.5% port· 1.41M sh· +$0 QoQ· Q2 2026
Clearbridge Investments, LLCAdded
Hedge Fund
$88.9M· 7.8% of total· 0.1% port· 725K sh· +$12.7M QoQ· Q2 2026
Duquesne Family Office LLCAdded
Family Office
$25.6M· 2.3% of total· 0.5% port· 209K sh· +$6.0M QoQ· Q2 2026
Fisher Asset Management, LLCReduced
Institutional Manager
$20.9M· 1.8% of total· 0.0% port· 171K sh· $-423K QoQ· Q2 2026
MARSHALL WACE, LLPReduced
Hedge Fund
$13.4M· 1.2% of total· 0.0% port· 109K sh· $-133.3M QoQ· Q2 2026
AXIOM INVESTORS LLC /DEReduced
Hedge Fund
$10.0M· 0.9% of total· 0.1% port· 82K sh· $-465K QoQ· Q2 2026
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPAdded
Hedge Fund
$5.5M· 0.5% of total· 0.0% port· 45K sh· QoQ· Q2 2026
ORBIMED ADVISORS LLCUnchanged
Hedge Fund
$5.2M· 0.5% of total· 0.1% port· 42K sh· +$0 QoQ· Q2 2026
Schonfeld Strategic Advisors LLCAdded
Hedge Fund
$3.4M· 0.3% of total· 0.0% port· 28K sh· QoQ· Q2 2026
Brevan Howard Capital Management LPAdded
Hedge Fund
$3.1M· 0.3% of total· 0.0% port· 25K sh· QoQ· Q2 2026
Gotham Asset Management, LLCReduced
Hedge Fund
$2.3M· 0.2% of total· 0.0% port· 19K sh· $-305K QoQ· Q2 2026
AQR CAPITAL MANAGEMENT LLCAdded
Hedge Fund
$1.6M· 0.1% of total· 0.0% port· 13K sh· +$1.6M QoQ· Q2 2026
Verition Fund Management LLCAdded
Hedge Fund
$1.2M· 0.1% of total· 0.0% port· 10K sh· QoQ· Q2 2026
Bridgewater Associates, LPAdded
Hedge Fund
$1.1M· 0.1% of total· 0.0% port· 9K sh· +$489K QoQ· Q2 2026
Holocene Advisors, LPReduced
Hedge Fund
$1.0M· 0.1% of total· 0.0% port· 8K sh· $-24.7M QoQ· Q2 2026
FRED ALGER MANAGEMENT, LLCAdded
Hedge Fund
$938K· 0.1% of total· 0.0% port· 8K sh· QoQ· Q2 2026
Rockefeller Capital Management L.P.Reduced
Hedge Fund
$591K· 0.1% of total· 0.0% port· 5K sh· $-447K QoQ· Q2 2026
BALYASNY ASSET MANAGEMENT LLCReduced
Hedge Fund
$441K· 0.0% of total· 0.0% port· 4K sh· $-12.0M QoQ· Q2 2026
Fulcrum Asset Management LLPAdded
Hedge Fund
$6K· 0.0% of total· 0.0% port· 46 sh· QoQ· Q2 2026
Walleye Capital LLCAdded
Hedge Fund
$123· 0.0% of total· 0.0% port· 1 sh· $-873K QoQ· Q2 2026
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