Stock Ownership/VRTX

Vertex Pharmaceuticals Inc (VRTX): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in VRTX · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
37
13F filers
Aggregate Value
$3.8B
Across holders
Last Price
$547.59
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity20 increased17 reduced4 exited
Full exits: CAXTON ASSOCIATES LLP, Qube Research & Technologies Ltd, PineBridge Investments, L.P., Magnetar Financial LLC
Institutional Holders of VRTX
↗
37 holders
Manager⇅Type⇅Shares⇅Market Value▼% of Total⇅% of Portfolio⇅Action⇅QoQ Change⇅Quarter⇅
Clearbridge Investments, LLC
CIK 0001348883
Hedge Fund2.34M$1.2B30.6%1.0%Reduced$-177.9MQ2 2026
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP
CIK 0001164508
Hedge Fund738K$366.8M9.7%0.2%Added+$49.4MQ2 2026
AQR CAPITAL MANAGEMENT LLC
CIK 0001167557
Hedge Fund616K$305.0M8.0%0.1%Added+$301.5MQ2 2026
MARSHALL WACE, LLP
CIK 0001318757
Hedge Fund544K$270.2M7.1%0.2%Added+$268.1MQ2 2026
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund510K$253.5M6.7%0.0%Added+$189.3MQ2 2026
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
Hedge Fund468K$232.7M6.1%0.1%Added+$205.6MQ2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
Hedge Fund394K$195.7M5.2%0.3%Added+$70.5MQ2 2026
Hudson Bay Capital Management LP
CIK 0001393825
Hedge Fund390K$193.9M5.1%0.5%Added+$149.2MQ2 2026
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
Hedge Fund320K$159.0M4.2%0.2%Reduced$-50.5MQ2 2026
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
Hedge Fund285K$141.6M3.7%0.1%Reduced+$141.1MQ2 2026
Clearbridge Investments, LLCReduced
Hedge Fund
$1.2B· 30.6% of total· 1.0% port· 2.34M sh· $-177.9M QoQ· Q2 2026
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPAdded
Hedge Fund
$366.8M· 9.7% of total· 0.2% port· 738K sh· +$49.4M QoQ· Q2 2026
AQR CAPITAL MANAGEMENT LLCAdded
Hedge Fund
$305.0M· 8.0% of total· 0.1% port· 616K sh· +$301.5M QoQ· Q2 2026
MARSHALL WACE, LLPAdded
Hedge Fund
$270.2M· 7.1% of total· 0.2% port· 544K sh· +$268.1M QoQ· Q2 2026
CITADEL ADVISORS LLCAdded
Hedge Fund
$253.5M· 6.7% of total· 0.0% port· 510K sh· +$189.3M QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCAdded
Hedge Fund
$232.7M· 6.1% of total· 0.1% port· 468K sh· +$205.6M QoQ· Q2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Added
Hedge Fund
$195.7M· 5.2% of total· 0.3% port· 394K sh· +$70.5M QoQ· Q2 2026
Hudson Bay Capital Management LPAdded
Hedge Fund
$193.9M· 5.1% of total· 0.5% port· 390K sh· +$149.2M QoQ· Q2 2026
RENAISSANCE TECHNOLOGIES LLCReduced
Hedge Fund
$159.0M· 4.2% of total· 0.2% port· 320K sh· $-50.5M QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPReduced
Hedge Fund
$141.6M· 3.7% of total· 0.1% port· 285K sh· +$141.1M QoQ· Q2 2026
BAILLIE GIFFORD & COAdded
Institutional Manager
$135.4M· 3.6% of total· 0.1% port· 273K sh· +$16.7M QoQ· Q2 2026
Rockefeller Capital Management L.P.Reduced
Hedge Fund
$74.2M· 2.0% of total· 0.1% port· 149K sh· $-358.5M QoQ· Q2 2026
BALYASNY ASSET MANAGEMENT LLCAdded
Hedge Fund
$72.0M· 1.9% of total· 0.1% port· 145K sh· +$68.9M QoQ· Q2 2026
Woodline Partners LPAdded
Hedge Fund
$69.7M· 1.8% of total· 0.2% port· 140K sh· +$2.6M QoQ· Q2 2026
Man Group plcReduced
Hedge Fund
$69.2M· 1.8% of total· 0.1% port· 139K sh· +$58.6M QoQ· Q2 2026
TWEEDY BROWNE CO LLC//Reduced
Institutional Manager
$19.9M· 0.5% of total· 1.5% port· 40K sh· $-132K QoQ· Q2 2026
TUDOR INVESTMENT CORP ET ALAdded
Hedge Fund
$15.0M· 0.4% of total· 0.0% port· 30K sh· +$13.8M QoQ· Q2 2026
Fisher Asset Management, LLCReduced
Institutional Manager
$12.2M· 0.3% of total· 0.0% port· 24K sh· $-3.3M QoQ· Q2 2026
Gotham Asset Management, LLCReduced
Hedge Fund
$9.4M· 0.2% of total· 0.0% port· 19K sh· $-944K QoQ· Q2 2026
Brevan Howard Capital Management LPAdded
Hedge Fund
$8.8M· 0.2% of total· 0.1% port· 18K sh· +$7.2M QoQ· Q2 2026
Holocene Advisors, LPReduced
Hedge Fund
$6.2M· 0.2% of total· 0.0% port· 12K sh· $-27.4M QoQ· Q2 2026
Squarepoint Ops LLCAdded
Hedge Fund
$6.0M· 0.2% of total· 0.0% port· 12K sh· +$2.2M QoQ· Q2 2026
Bridgewater Associates, LPReduced
Hedge Fund
$5.4M· 0.1% of total· 0.0% port· 11K sh· $-1.2M QoQ· Q2 2026
TCW GROUP INCAdded
Hedge Fund
$2.1M· 0.1% of total· 0.0% port· 4K sh· +$37K QoQ· Q2 2026
Pinpoint Asset Management LtdReduced
Hedge Fund
$1.7M· 0.0% of total· 0.3% port· 4K sh· $-1.9M QoQ· Q1 2025
SHAW D E & CO INCReduced
Hedge Fund
$1.5M· 0.0% of total· 0.0% port· 3K sh· $-122.1M QoQ· Q2 2026
FRED ALGER MANAGEMENT, LLCAdded
Hedge Fund
$1.5M· 0.0% of total· 0.0% port· 3K sh· +$268K QoQ· Q2 2026
Schonfeld Strategic Advisors LLCAdded
Hedge Fund
$1.4M· 0.0% of total· 0.0% port· 3K sh· — QoQ· Q2 2026
Point72 Asset Management, L.P.Added
Hedge Fund
$1.3M· 0.0% of total· 0.0% port· 3K sh· $-484K QoQ· Q2 2026
CAPSTONE INVESTMENT ADVISORS, LLCReduced
Hedge Fund
$719K· 0.0% of total· 0.0% port· 1K sh· $-11.2M QoQ· Q2 2026
Ancora Advisors, LLCAdded
Hedge Fund
$560K· 0.0% of total· 0.0% port· 1K sh· +$38K QoQ· Q2 2026
Bridgewater Advisors Inc.Reduced
Hedge Fund
$519K· 0.0% of total· 0.0% port· 1K sh· $-3K QoQ· Q2 2026
Parallax Volatility Advisers, L.P.Added
Hedge Fund
$298K· 0.0% of total· 0.0% port· 599 sh· — QoQ· Q2 2026
JUPITER ASSET MANAGEMENT LTDAdded
Hedge Fund
$290K· 0.0% of total· 0.0% port· 583 sh· — QoQ· Q2 2026
Verition Fund Management LLCReduced
Hedge Fund
$213K· 0.0% of total· 0.0% port· 429 sh· $-487K QoQ· Q2 2026
Walleye Capital LLCReduced
Hedge Fund
$166K· 0.0% of total· 0.0% port· 335 sh· $-4.8M QoQ· Q2 2026
Alphadyne Asset Management LPReduced
Hedge Fund
$36K· 0.0% of total· 0.0% port· 73 sh· $-11.2M QoQ· Q2 2026
1–10 of 37
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