VERTEX PHARMACEUTICALS INC (VRTX): Institutional Ownership

Hedge funds and institutional managers reporting a position in VRTX · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
28
13F filers
Aggregate Value
$700.9M
Across holders
Last Price
$491.34
2026-06-26
Sector
Health Care
GICS
Holder activity5 new10 added13 reduced
Institutional Holders of VRTX
28 holders
ManagerTypeSharesMarket Value% of Total% of PortfolioActionQoQ ChangeQuarter
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
Hedge Fund422K$188.3M26.9%0.3%Reduced$-37.2MQ1 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
Hedge Fund252K$112.5M16.1%0.2%Reduced$-9.1MQ1 2026
Man Group plc
CIK 0001637460
Hedge Fund226K$101.0M14.4%0.2%Added+$82.9MQ1 2026
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund224K$100.1M14.3%0.0%Added+$48.9MQ1 2026
Holocene Advisors, LP
CIK 0001700574
Hedge Fund68K$30.2M4.3%0.1%Added+$29.5MQ1 2026
BAILLIE GIFFORD & CO
CIK 0001088875
Institutional Manager57K$25.6M3.7%0.0%Added+$12.7MQ1 2026
Hudson Bay Capital Management LP
CIK 0001393825
Hedge Fund45K$20.1M2.9%0.1%Reduced$-53.4MQ1 2026
TWEEDY BROWNE CO LLC//
CIK 0000732905
Institutional Manager40K$18.0M2.6%1.4%Added+$553KQ1 2026
CAXTON ASSOCIATES LLP
CIK 0002051323
Hedge Fund36K$16.1M2.3%0.4%NewQ1 2026
Eisler Capital (UK) Ltd.
CIK 0001849486
Hedge Fund31K$14.3M2.0%0.1%Reduced$-33.6MQ3 2024
Fisher Asset Management, LLC
CIK 0000850529
Institutional Manager31K$13.9M2.0%0.0%Added+$2.7MQ1 2026
Walleye Capital LLC
CIK 0001758720
Hedge Fund31K$13.7M2.0%0.1%Added+$7.2MQ1 2026
BALYASNY ASSET MANAGEMENT LLC
CIK 0001218710
Hedge Fund24K$10.6M1.5%0.0%Reduced$-40.1MQ1 2026
ExodusPoint Capital Management, LP
CIK 0001736225
Hedge Fund22K$10.0M1.4%0.1%NewQ1 2026
Gotham Asset Management, LLC
CIK 0001510387
Hedge Fund21K$9.3M1.3%0.0%Reduced$-279KQ1 2026
Bridgewater Associates, LP
CIK 0001350694
Hedge Fund13K$6.0M0.9%0.0%Reduced$-6.3MQ1 2026
Qube Research & Technologies Ltd
CIK 0001729829
Hedge Fund10K$4.6M0.6%0.0%Reduced$-7.1MQ1 2026
Pinpoint Asset Management Ltd
CIK 0001803237
Hedge Fund4K$1.7M0.2%0.3%Reduced$-1.9MQ1 2025
Brevan Howard Capital Management LP
CIK 0001512857
Hedge Fund3K$1.4M0.2%0.0%NewQ1 2026
TUDOR INVESTMENT CORP ET AL
CIK 0000923093
Hedge Fund2K$714K0.1%0.0%Reduced$-4.7MQ1 2026
RENAISSANCE TECHNOLOGIES LLCReduced
Hedge Fund
$188.3M· 26.9% of total· 0.3% port· 422K sh· $-37.2M QoQ· Q1 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Reduced
Hedge Fund
$112.5M· 16.1% of total· 0.2% port· 252K sh· $-9.1M QoQ· Q1 2026
Man Group plcAdded
Hedge Fund
$101.0M· 14.4% of total· 0.2% port· 226K sh· +$82.9M QoQ· Q1 2026
CITADEL ADVISORS LLCAdded
Hedge Fund
$100.1M· 14.3% of total· 0.0% port· 224K sh· +$48.9M QoQ· Q1 2026
Holocene Advisors, LPAdded
Hedge Fund
$30.2M· 4.3% of total· 0.1% port· 68K sh· +$29.5M QoQ· Q1 2026
BAILLIE GIFFORD & COAdded
Institutional Manager
$25.6M· 3.7% of total· 0.0% port· 57K sh· +$12.7M QoQ· Q1 2026
Hudson Bay Capital Management LPReduced
Hedge Fund
$20.1M· 2.9% of total· 0.1% port· 45K sh· $-53.4M QoQ· Q1 2026
TWEEDY BROWNE CO LLC//Added
Institutional Manager
$18.0M· 2.6% of total· 1.4% port· 40K sh· +$553K QoQ· Q1 2026
CAXTON ASSOCIATES LLPNew
Hedge Fund
$16.1M· 2.3% of total· 0.4% port· 36K sh· QoQ· Q1 2026
Eisler Capital (UK) Ltd.Reduced
Hedge Fund
$14.3M· 2.0% of total· 0.1% port· 31K sh· $-33.6M QoQ· Q3 2024
Fisher Asset Management, LLCAdded
Institutional Manager
$13.9M· 2.0% of total· 0.0% port· 31K sh· +$2.7M QoQ· Q1 2026
Walleye Capital LLCAdded
Hedge Fund
$13.7M· 2.0% of total· 0.1% port· 31K sh· +$7.2M QoQ· Q1 2026
BALYASNY ASSET MANAGEMENT LLCReduced
Hedge Fund
$10.6M· 1.5% of total· 0.0% port· 24K sh· $-40.1M QoQ· Q1 2026
ExodusPoint Capital Management, LPNew
Hedge Fund
$10.0M· 1.4% of total· 0.1% port· 22K sh· QoQ· Q1 2026
Gotham Asset Management, LLCReduced
Hedge Fund
$9.3M· 1.3% of total· 0.0% port· 21K sh· $-279K QoQ· Q1 2026
Bridgewater Associates, LPReduced
Hedge Fund
$6.0M· 0.9% of total· 0.0% port· 13K sh· $-6.3M QoQ· Q1 2026
Qube Research & Technologies LtdReduced
Hedge Fund
$4.6M· 0.6% of total· 0.0% port· 10K sh· $-7.1M QoQ· Q1 2026
Pinpoint Asset Management LtdReduced
Hedge Fund
$1.7M· 0.2% of total· 0.3% port· 4K sh· $-1.9M QoQ· Q1 2025
Brevan Howard Capital Management LPNew
Hedge Fund
$1.4M· 0.2% of total· 0.0% port· 3K sh· QoQ· Q1 2026
TUDOR INVESTMENT CORP ET ALReduced
Hedge Fund
$714K· 0.1% of total· 0.0% port· 2K sh· $-4.7M QoQ· Q1 2026
Verition Fund Management LLCReduced
Hedge Fund
$629K· 0.1% of total· 0.0% port· 1K sh· $-3.1M QoQ· Q1 2026
Bridgewater Advisors Inc.Added
Hedge Fund
$503K· 0.1% of total· 0.0% port· 1K sh· +$15K QoQ· Q1 2026
Ancora Advisors, LLCAdded
Hedge Fund
$469K· 0.1% of total· 0.0% port· 1K sh· +$67K QoQ· Q1 2026
TWO SIGMA INVESTMENTS, LPReduced
Hedge Fund
$447K· 0.1% of total· 0.0% port· 1K sh· $-1.4M QoQ· Q1 2026
ICONIQ Capital, LLCNew
Family Office
$352K· 0.1% of total· 0.0% port· 790 sh· QoQ· Q2 2025
MARSHALL WACE, LLPReduced
Hedge Fund
$268K· 0.0% of total· 0.0% port· 600 sh· $-89K QoQ· Q1 2026
GAMCO INVESTORS, INC. ET ALNew
Institutional Manager
$201K· 0.0% of total· 0.0% port· 512 sh· QoQ· Q3 2025
AQR CAPITAL MANAGEMENT LLCAdded
Hedge Fund
$6K· 0.0% of total· 0.0% port· 14 sh· +$3K QoQ· Q1 2026
120 of 28
1 / 2