Design Therapeutics, Inc. (DSGN): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in DSGN · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
14
13F filers
Aggregate Value
$105.4M
Across holders
Last Price
$15.23
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity7 increased6 reduced2 exited
Full exits: MARSHALL WACE, LLP, Brevan Howard Capital Management LP
Institutional Holders of DSGN
14 holders
ManagerTypeSharesMarket Value% of Total% of PortfolioActionQoQ ChangeQuarter
BAKER BROS. ADVISORS LP
CIK 0001263508
Hedge Fund2.68M$38.8M36.8%0.2%Added+$1.3MQ2 2026
Point72 Asset Management, L.P.
CIK 0001603466
Hedge Fund2.37M$34.2M32.5%0.0%Reduced$-5.2MQ2 2026
Woodline Partners LP
CIK 0001784547
Hedge Fund700K$10.1M9.6%0.0%Reduced$-3.8MQ2 2026
Qube Research & Technologies Ltd
CIK 0001729829
Hedge Fund437K$6.3M6.0%0.0%Added+$5.8MQ2 2026
RENAISSANCE TECHNOLOGIES LLC
CIK 0001037389
Hedge Fund388K$5.6M5.3%0.0%Reduced$-294KQ2 2026
SHAW D E & CO INC
CIK 0001009207
Hedge Fund196K$2.8M2.7%0.0%Reduced+$1.9MQ2 2026
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
Hedge Fund148K$2.1M2.0%0.0%Added+$561KQ2 2026
BALYASNY ASSET MANAGEMENT LLC
CIK 0001218710
Hedge Fund111K$1.6M1.5%0.0%AddedQ2 2026
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund82K$1.2M1.1%0.0%Reduced$-2.1MQ2 2026
AQR CAPITAL MANAGEMENT LLC
CIK 0001167557
Hedge Fund71K$1.0M1.0%0.0%Added+$1.0MQ2 2026
BAKER BROS. ADVISORS LPAdded
Hedge Fund
$38.8M· 36.8% of total· 0.2% port· 2.68M sh· +$1.3M QoQ· Q2 2026
Point72 Asset Management, L.P.Reduced
Hedge Fund
$34.2M· 32.5% of total· 0.0% port· 2.37M sh· $-5.2M QoQ· Q2 2026
Woodline Partners LPReduced
Hedge Fund
$10.1M· 9.6% of total· 0.0% port· 700K sh· $-3.8M QoQ· Q2 2026
Qube Research & Technologies LtdAdded
Hedge Fund
$6.3M· 6.0% of total· 0.0% port· 437K sh· +$5.8M QoQ· Q2 2026
RENAISSANCE TECHNOLOGIES LLCReduced
Hedge Fund
$5.6M· 5.3% of total· 0.0% port· 388K sh· $-294K QoQ· Q2 2026
SHAW D E & CO INCReduced
Hedge Fund
$2.8M· 2.7% of total· 0.0% port· 196K sh· +$1.9M QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCAdded
Hedge Fund
$2.1M· 2.0% of total· 0.0% port· 148K sh· +$561K QoQ· Q2 2026
BALYASNY ASSET MANAGEMENT LLCAdded
Hedge Fund
$1.6M· 1.5% of total· 0.0% port· 111K sh· QoQ· Q2 2026
CITADEL ADVISORS LLCReduced
Hedge Fund
$1.2M· 1.1% of total· 0.0% port· 82K sh· $-2.1M QoQ· Q2 2026
AQR CAPITAL MANAGEMENT LLCAdded
Hedge Fund
$1.0M· 1.0% of total· 0.0% port· 71K sh· +$1.0M QoQ· Q2 2026
ExodusPoint Capital Management, LPAdded
Hedge Fund
$597K· 0.6% of total· 0.0% port· 41K sh· QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPAdded
Hedge Fund
$476K· 0.5% of total· 0.0% port· 33K sh· +$241K QoQ· Q2 2026
Squarepoint Ops LLCReduced
Hedge Fund
$429K· 0.4% of total· 0.0% port· 30K sh· $-817K QoQ· Q2 2026
Rockefeller Capital Management L.P.Unchanged
Hedge Fund
$53K· 0.1% of total· 0.0% port· 4K sh· $-32K QoQ· Q2 2026
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