Stock Ownership/GPCR

STRUCTURE THERAPEUTICS INC (GPCR): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in GPCR · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
19
13F filers
Aggregate Value
$292.8M
Across holders
Last Price
$49.01
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity12 increased6 reduced5 exited
Full exits: RENAISSANCE TECHNOLOGIES LLC, BALYASNY ASSET MANAGEMENT LLC, Holocene Advisors, LP, Pentwater Capital Management LP, Walleye Capital LLC
Institutional Holders of GPCR
↗
19 holders
Manager⇅Type⇅Shares⇅Market Value▼% of Total⇅% of Portfolio⇅Action⇅QoQ Change⇅Quarter⇅
ORBIMED ADVISORS LLC
CIK 0001055951
Hedge Fund2.21M$118.6M40.5%2.2%Added+$39.4MQ2 2026
BAKER BROS. ADVISORS LP
CIK 0001263508
Hedge Fund1.43M$76.9M26.3%0.4%Unchanged+$0Q2 2026
MARSHALL WACE, LLP
CIK 0001318757
Hedge Fund268K$14.4M4.9%0.0%Added+$12.1MQ2 2026
TWO SIGMA INVESTMENTS, LP
CIK 0001179392
Hedge Fund204K$11.0M3.7%0.0%Added+$1.2MQ2 2026
Schonfeld Strategic Advisors LLC
CIK 0001665241
Hedge Fund191K$10.2M3.5%0.0%Added+$1.4MQ2 2026
Woodline Partners LP
CIK 0001784547
Hedge Fund154K$8.3M2.8%0.0%Reduced$-2.0MQ2 2026
ArrowMark Colorado Holdings LLC
CIK 0001483859
Hedge Fund151K$8.1M2.8%0.3%Reduced$-2.0MQ2 2026
Squarepoint Ops LLC
CIK 0001642575
Hedge Fund126K$6.7M2.3%0.0%Added+$5.5MQ2 2026
SHAW D E & CO INC
CIK 0001009207
Hedge Fund115K$6.2M2.1%0.0%Reduced$-4.8MQ2 2026
VOLORIDGE INVESTMENT MANAGEMENT, LLC
CIK 0001556921
Hedge Fund112K$6.0M2.1%0.0%Reduced$-7.7MQ2 2026
ORBIMED ADVISORS LLCAdded
Hedge Fund
$118.6M· 40.5% of total· 2.2% port· 2.21M sh· +$39.4M QoQ· Q2 2026
BAKER BROS. ADVISORS LPUnchanged
Hedge Fund
$76.9M· 26.3% of total· 0.4% port· 1.43M sh· +$0 QoQ· Q2 2026
MARSHALL WACE, LLPAdded
Hedge Fund
$14.4M· 4.9% of total· 0.0% port· 268K sh· +$12.1M QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPAdded
Hedge Fund
$11.0M· 3.7% of total· 0.0% port· 204K sh· +$1.2M QoQ· Q2 2026
Schonfeld Strategic Advisors LLCAdded
Hedge Fund
$10.2M· 3.5% of total· 0.0% port· 191K sh· +$1.4M QoQ· Q2 2026
Woodline Partners LPReduced
Hedge Fund
$8.3M· 2.8% of total· 0.0% port· 154K sh· $-2.0M QoQ· Q2 2026
ArrowMark Colorado Holdings LLCReduced
Hedge Fund
$8.1M· 2.8% of total· 0.3% port· 151K sh· $-2.0M QoQ· Q2 2026
Squarepoint Ops LLCAdded
Hedge Fund
$6.7M· 2.3% of total· 0.0% port· 126K sh· +$5.5M QoQ· Q2 2026
SHAW D E & CO INCReduced
Hedge Fund
$6.2M· 2.1% of total· 0.0% port· 115K sh· $-4.8M QoQ· Q2 2026
VOLORIDGE INVESTMENT MANAGEMENT, LLCReduced
Hedge Fund
$6.0M· 2.1% of total· 0.0% port· 112K sh· $-7.7M QoQ· Q2 2026
Qube Research & Technologies LtdAdded
Hedge Fund
$5.0M· 1.7% of total· 0.0% port· 93K sh· +$1.1M QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCReduced
Hedge Fund
$4.8M· 1.6% of total· 0.0% port· 90K sh· $-4.3M QoQ· Q2 2026
ExodusPoint Capital Management, LPAdded
Hedge Fund
$4.2M· 1.4% of total· 0.0% port· 78K sh· — QoQ· Q2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Added
Hedge Fund
$4.0M· 1.4% of total· 0.0% port· 75K sh· — QoQ· Q2 2026
Brevan Howard Capital Management LPAdded
Hedge Fund
$3.3M· 1.1% of total· 0.0% port· 60K sh· +$706K QoQ· Q2 2026
TUDOR INVESTMENT CORP ET ALReduced
Hedge Fund
$2.9M· 1.0% of total· 0.0% port· 54K sh· $-1.2M QoQ· Q2 2026
Verition Fund Management LLCAdded
Hedge Fund
$1.5M· 0.5% of total· 0.0% port· 29K sh· +$24K QoQ· Q2 2026
Fulcrum Asset Management LLPAdded
Hedge Fund
$685K· 0.2% of total· 0.1% port· 13K sh· — QoQ· Q2 2026
Rockefeller Capital Management L.P.Added
Hedge Fund
$135K· 0.0% of total· 0.0% port· 3K sh· +$16K QoQ· Q2 2026
1–10 of 19
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