IONIS PHARMACEUTICALS INC (IONS): Institutional Ownership
Hedge funds and institutional managers reporting a position in IONS · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.
Reported Holders
21
13F filers
Aggregate Value
$752.7M
Across holders
Last Price
$81.18
2026-06-26
Sector
Health Care
GICS
Holder activity5 new10 added6 reduced
| Manager⇅ | Type⇅ | Shares⇅ | Market Value▼ | % of Total⇅ | % of Portfolio⇅ | Action⇅ | QoQ Change⇅ | Quarter⇅ |
|---|---|---|---|---|---|---|---|---|
| TWO SIGMA INVESTMENTS, LP CIK 0001179392 | Hedge Fund | 5.86M | $439.8M | 58.4% | 0.4% | Added | +$240.2M | Q1 2026 |
| TWEEDY BROWNE CO LLC// CIK 0000732905 | Institutional Manager | 2.28M | $170.9M | 22.7% | 13.6% | Reduced | $-14.2M | Q1 2026 |
| CITADEL ADVISORS LLC CIK 0001423053 | Hedge Fund | 577K | $43.4M | 5.8% | 0.0% | Added | +$38.2M | Q1 2026 |
| RENAISSANCE TECHNOLOGIES LLC CIK 0001037389 | Hedge Fund | 306K | $22.9M | 3.0% | 0.0% | Added | +$6.2M | Q1 2026 |
| ExodusPoint Capital Management, LP CIK 0001736225 | Hedge Fund | 227K | $17.1M | 2.3% | 0.1% | Added | +$10.8M | Q1 2026 |
| Schonfeld Strategic Advisors LLC CIK 0001665241 | Hedge Fund | 201K | $13.1M | 1.7% | 0.1% | New | — | Q3 2025 |
| Fisher Asset Management, LLC CIK 0000850529 | Institutional Manager | 142K | $10.6M | 1.4% | 0.0% | Reduced | $-5K | Q1 2026 |
| Gotham Asset Management, LLC CIK 0001510387 | Hedge Fund | 99K | $7.4M | 1.0% | 0.0% | Added | +$4.2M | Q1 2026 |
| Bridgewater Associates, LP CIK 0001350694 | Hedge Fund | 68K | $5.4M | 0.7% | 0.0% | Added | +$1.9M | Q4 2025 |
| Walleye Capital LLC CIK 0001758720 | Hedge Fund | 66K | $5.0M | 0.7% | 0.0% | Added | +$4.1M | Q1 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 0001165408 | Hedge Fund | 50K | $3.8M | 0.5% | 0.0% | Reduced | $-6.8M | Q1 2026 |
| TUDOR INVESTMENT CORP ET AL CIK 0000923093 | Hedge Fund | 48K | $3.6M | 0.5% | 0.0% | Added | +$3.3M | Q1 2026 |
| Qube Research & Technologies Ltd CIK 0001729829 | Hedge Fund | 43K | $3.2M | 0.4% | 0.0% | New | — | Q1 2026 |
| AQR CAPITAL MANAGEMENT LLC CIK 0001167557 | Hedge Fund | 28K | $2.1M | 0.3% | 0.0% | Added | +$2.1M | Q1 2026 |
| MARSHALL WACE, LLP CIK 0001318757 | Hedge Fund | 25K | $1.9M | 0.3% | 0.0% | Reduced | $-17.4M | Q1 2026 |
| Verition Fund Management LLC CIK 0001454027 | Hedge Fund | 23K | $1.8M | 0.2% | 0.0% | New | — | Q4 2025 |
| Brevan Howard Capital Management LP CIK 0001512857 | Hedge Fund | 5K | $295K | 0.0% | 0.0% | New | — | Q3 2025 |
| Ancora Advisors, LLC CIK 0001446114 | Hedge Fund | 2K | $180K | 0.0% | 0.0% | Added | +$4K | Q1 2026 |
| Man Group plc CIK 0001637460 | Hedge Fund | 2K | $135K | 0.0% | 0.0% | Reduced | $-12.3M | Q1 2026 |
| BALYASNY ASSET MANAGEMENT LLC CIK 0001218710 | Hedge Fund | 149 | $12K | 0.0% | 0.0% | New | — | Q4 2025 |
Added
Hedge Fund
$439.8M· 58.4% of total· 0.4% port· 5.86M sh· +$240.2M QoQ· Q1 2026
Reduced
Institutional Manager
$170.9M· 22.7% of total· 13.6% port· 2.28M sh· $-14.2M QoQ· Q1 2026
Added
Hedge Fund
$43.4M· 5.8% of total· 0.0% port· 577K sh· +$38.2M QoQ· Q1 2026
Added
Hedge Fund
$22.9M· 3.0% of total· 0.0% port· 306K sh· +$6.2M QoQ· Q1 2026
Added
Hedge Fund
$17.1M· 2.3% of total· 0.1% port· 227K sh· +$10.8M QoQ· Q1 2026
New
Hedge Fund
$13.1M· 1.7% of total· 0.1% port· 201K sh· — QoQ· Q3 2025
Reduced
Institutional Manager
$10.6M· 1.4% of total· 0.0% port· 142K sh· $-5K QoQ· Q1 2026
Added
Hedge Fund
$7.4M· 1.0% of total· 0.0% port· 99K sh· +$4.2M QoQ· Q1 2026
Added
Hedge Fund
$5.4M· 0.7% of total· 0.0% port· 68K sh· +$1.9M QoQ· Q4 2025
Added
Hedge Fund
$5.0M· 0.7% of total· 0.0% port· 66K sh· +$4.1M QoQ· Q1 2026
Reduced
Hedge Fund
$3.8M· 0.5% of total· 0.0% port· 50K sh· $-6.8M QoQ· Q1 2026
Added
Hedge Fund
$3.6M· 0.5% of total· 0.0% port· 48K sh· +$3.3M QoQ· Q1 2026
New
Hedge Fund
$3.2M· 0.4% of total· 0.0% port· 43K sh· — QoQ· Q1 2026
Added
Hedge Fund
$2.1M· 0.3% of total· 0.0% port· 28K sh· +$2.1M QoQ· Q1 2026
Reduced
Hedge Fund
$1.9M· 0.3% of total· 0.0% port· 25K sh· $-17.4M QoQ· Q1 2026
New
Hedge Fund
$1.8M· 0.2% of total· 0.0% port· 23K sh· — QoQ· Q4 2025
New
Hedge Fund
$295K· 0.0% of total· 0.0% port· 5K sh· — QoQ· Q3 2025
Added
Hedge Fund
$180K· 0.0% of total· 0.0% port· 2K sh· +$4K QoQ· Q1 2026
Reduced
Hedge Fund
$135K· 0.0% of total· 0.0% port· 2K sh· $-12.3M QoQ· Q1 2026
New
Hedge Fund
$12K· 0.0% of total· 0.0% port· 149 sh· — QoQ· Q4 2025
Reduced
Hedge Fund
$8K· 0.0% of total· 0.0% port· 100 sh· $-35.7M QoQ· Q1 2026
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