Praxis Precision Medicines, Inc. (PRAX): Ownership & Insider Activity
Hedge funds and institutional managers reporting a position in PRAX · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.
Reported Holders
22
13F filers
Aggregate Value
$1.3B
Across holders
Last Price
$368.03
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity16 increased3 reduced2 exited
Full exits: Hudson Bay Capital Management LP, Tetragon Partners GP Ltd
| Manager⇅ | Type⇅ | Shares⇅ | Market Value▼ | % of Total⇅ | % of Portfolio⇅ | Action⇅ | QoQ Change⇅ | Quarter⇅ |
|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP CIK 0001263508 | Hedge Fund | 1.75M | $587.0M | 46.9% | 2.9% | Unchanged | +$0 | Q2 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 0001165408 | Hedge Fund | 1.02M | $340.0M | 27.2% | 0.5% | Added | +$66.9M | Q2 2026 |
| ORBIMED ADVISORS LLC CIK 0001055951 | Hedge Fund | 230K | $77.0M | 6.2% | 1.4% | Added | +$19.3M | Q2 2026 |
| Woodline Partners LP CIK 0001784547 | Hedge Fund | 200K | $67.0M | 5.4% | 0.2% | Unchanged | +$0 | Q2 2026 |
| Qube Research & Technologies Ltd CIK 0001729829 | Hedge Fund | 152K | $51.0M | 4.1% | 0.0% | Added | +$8.1M | Q2 2026 |
| MARSHALL WACE, LLP CIK 0001318757 | Hedge Fund | 137K | $45.9M | 3.7% | 0.0% | Added | +$45.8M | Q2 2026 |
| AQR CAPITAL MANAGEMENT LLC CIK 0001167557 | Hedge Fund | 58K | $19.6M | 1.6% | 0.0% | Reduced | +$19.5M | Q2 2026 |
| ArrowMark Colorado Holdings LLC CIK 0001483859 | Hedge Fund | 46K | $15.4M | 1.2% | 0.6% | Reduced | $-24.0M | Q2 2026 |
| Squarepoint Ops LLC CIK 0001642575 | Hedge Fund | 43K | $14.2M | 1.1% | 0.0% | Added | +$13.6M | Q2 2026 |
| Clearbridge Investments, LLC CIK 0001348883 | Hedge Fund | 28K | $9.4M | 0.7% | 0.0% | Added | — | Q2 2026 |
Unchanged
Hedge Fund
$587.0M· 46.9% of total· 2.9% port· 1.75M sh· +$0 QoQ· Q2 2026
Added
Hedge Fund
$340.0M· 27.2% of total· 0.5% port· 1.02M sh· +$66.9M QoQ· Q2 2026
Added
Hedge Fund
$77.0M· 6.2% of total· 1.4% port· 230K sh· +$19.3M QoQ· Q2 2026
Unchanged
Hedge Fund
$67.0M· 5.4% of total· 0.2% port· 200K sh· +$0 QoQ· Q2 2026
Added
Hedge Fund
$51.0M· 4.1% of total· 0.0% port· 152K sh· +$8.1M QoQ· Q2 2026
Added
Hedge Fund
$45.9M· 3.7% of total· 0.0% port· 137K sh· +$45.8M QoQ· Q2 2026
Reduced
Hedge Fund
$19.6M· 1.6% of total· 0.0% port· 58K sh· +$19.5M QoQ· Q2 2026
Reduced
Hedge Fund
$15.4M· 1.2% of total· 0.6% port· 46K sh· $-24.0M QoQ· Q2 2026
Added
Hedge Fund
$14.2M· 1.1% of total· 0.0% port· 43K sh· +$13.6M QoQ· Q2 2026
Added
Hedge Fund
$9.4M· 0.7% of total· 0.0% port· 28K sh· — QoQ· Q2 2026
Added
Hedge Fund
$7.1M· 0.6% of total· 0.0% port· 21K sh· +$6.0M QoQ· Q2 2026
Added
Hedge Fund
$6.3M· 0.5% of total· 0.0% port· 19K sh· +$388K QoQ· Q2 2026
Added
Hedge Fund
$3.5M· 0.3% of total· 0.0% port· 10K sh· — QoQ· Q2 2026
Added
Hedge Fund
$2.5M· 0.2% of total· 0.0% port· 7K sh· $-9.5M QoQ· Q2 2026
Added
Hedge Fund
$1.7M· 0.1% of total· 0.0% port· 5K sh· $-1.6M QoQ· Q2 2026
Added
Hedge Fund
$731K· 0.1% of total· 0.0% port· 2K sh· +$229K QoQ· Q2 2026
Added
Hedge Fund
$640K· 0.1% of total· 0.0% port· 2K sh· — QoQ· Q2 2026
Added
Hedge Fund
$629K· 0.1% of total· 0.0% port· 2K sh· — QoQ· Q2 2026
Added
Hedge Fund
$495K· 0.0% of total· 0.0% port· 1K sh· +$169K QoQ· Q2 2026
Added
Hedge Fund
$352K· 0.0% of total· 0.0% port· 1K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$333K· 0.0% of total· 0.0% port· 995 sh· $-949K QoQ· Q2 2026
Unchanged
Hedge Fund
$105K· 0.0% of total· 0.0% port· 315 sh· +$103K QoQ· Q2 2026
1–10 of 22
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