Stock Ownership/SKYE

Skye Bioscience, Inc. (SKYE): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in SKYE · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders

13F filers

Aggregate Value

$1.3M

Across holders

Last Price

$2.17

2026-08-24

Sector

Health Care

GICS

Quarterly fund activity1 increased1 reduced1 exited

Full exits: TWO SIGMA INVESTMENTS, LP

Institutional Holders of SKYE

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4 holders

Manager⇅	Type⇅	Shares⇅	Market Value▼	% of Total⇅	% of Portfolio⇅	Action⇅	QoQ Change⇅	Quarter⇅
BAKER BROS. ADVISORS LP CIK 0001263508	Hedge Fund	1.58M	$1.1M	86.7%	0.0%	Unchanged	+$0	Q2 2026
MILLENNIUM MANAGEMENT LLC CIK 0001273087	Hedge Fund	199K	$138K	10.9%	0.0%	Reduced	$-41K	Q2 2026
Qube Research & Technologies Ltd CIK 0001729829	Hedge Fund	43K	$30K	2.4%	0.0%	Added	—	Q2 2026
Rockefeller Capital Management L.P. CIK 0001739439	Hedge Fund	39	$27	0.0%	0.0%	Unchanged	+$0	Q2 2026

BAKER BROS. ADVISORS LPUnchanged

Hedge Fund

$1.1M· 86.7% of total· 0.0% port· 1.58M sh· +$0 QoQ· Q2 2026

MILLENNIUM MANAGEMENT LLCReduced

Hedge Fund

$138K· 10.9% of total· 0.0% port· 199K sh· $-41K QoQ· Q2 2026

Qube Research & Technologies LtdAdded

Hedge Fund

$30K· 2.4% of total· 0.0% port· 43K sh· — QoQ· Q2 2026

Rockefeller Capital Management L.P.Unchanged

Hedge Fund

$27· 0.0% of total· 0.0% port· 39 sh· +$0 QoQ· Q2 2026

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