SPYRE THERAPEUTICS INC (SYRE): Institutional Ownership
Hedge funds and institutional managers reporting a position in SYRE · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.
Reported Holders
13
13F filers
Aggregate Value
$25.8M
Across holders
Last Price
$87.89
2026-06-26
Sector
Health Care
GICS
Holder activity8 new3 added2 reduced
| Manager⇅ | Type⇅ | Shares⇅ | Market Value▼ | % of Total⇅ | % of Portfolio⇅ | Action⇅ | QoQ Change⇅ | Quarter⇅ |
|---|---|---|---|---|---|---|---|---|
| ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 0001165408 | Hedge Fund | 610K | $9.1M | 35.4% | 0.0% | New | — | Q2 2025 |
| CITADEL ADVISORS LLC CIK 0001423053 | Hedge Fund | 108K | $5.5M | 21.1% | 0.0% | Added | +$4.2M | Q1 2026 |
| ExodusPoint Capital Management, LP CIK 0001736225 | Hedge Fund | 87K | $4.4M | 17.0% | 0.0% | Added | +$2.5M | Q1 2026 |
| BALYASNY ASSET MANAGEMENT LLC CIK 0001218710 | Hedge Fund | 55K | $2.8M | 10.8% | 0.0% | Reduced | $-907K | Q1 2026 |
| Schonfeld Strategic Advisors LLC CIK 0001665241 | Hedge Fund | 81K | $1.4M | 5.3% | 0.0% | New | — | Q3 2025 |
| Verition Fund Management LLC CIK 0001454027 | Hedge Fund | 48K | $813K | 3.1% | 0.0% | New | — | Q3 2025 |
| Man Group plc CIK 0001637460 | Hedge Fund | 10K | $482K | 1.9% | 0.0% | New | — | Q1 2026 |
| RENAISSANCE TECHNOLOGIES LLC CIK 0001037389 | Hedge Fund | 31K | $463K | 1.8% | 0.0% | New | — | Q2 2025 |
| TUDOR INVESTMENT CORP ET AL CIK 0000923093 | Hedge Fund | 8K | $422K | 1.6% | 0.0% | Reduced | $-89K | Q1 2026 |
| TWO SIGMA INVESTMENTS, LP CIK 0001179392 | Hedge Fund | 10K | $224K | 0.9% | 0.0% | New | — | Q4 2024 |
| Brevan Howard Capital Management LP CIK 0001512857 | Hedge Fund | 6K | $203K | 0.8% | 0.0% | New | — | Q4 2025 |
| MARSHALL WACE, LLP CIK 0001318757 | Hedge Fund | 800 | $40K | 0.2% | 0.0% | New | — | Q1 2026 |
| AQR CAPITAL MANAGEMENT LLC CIK 0001167557 | Hedge Fund | 245 | $12K | 0.0% | 0.0% | Added | +$10K | Q1 2026 |
New
Hedge Fund
$9.1M· 35.4% of total· 0.0% port· 610K sh· — QoQ· Q2 2025
Added
Hedge Fund
$5.5M· 21.1% of total· 0.0% port· 108K sh· +$4.2M QoQ· Q1 2026
Added
Hedge Fund
$4.4M· 17.0% of total· 0.0% port· 87K sh· +$2.5M QoQ· Q1 2026
Reduced
Hedge Fund
$2.8M· 10.8% of total· 0.0% port· 55K sh· $-907K QoQ· Q1 2026
New
Hedge Fund
$1.4M· 5.3% of total· 0.0% port· 81K sh· — QoQ· Q3 2025
New
Hedge Fund
$813K· 3.1% of total· 0.0% port· 48K sh· — QoQ· Q3 2025
New
Hedge Fund
$482K· 1.9% of total· 0.0% port· 10K sh· — QoQ· Q1 2026
New
Hedge Fund
$463K· 1.8% of total· 0.0% port· 31K sh· — QoQ· Q2 2025
Reduced
Hedge Fund
$422K· 1.6% of total· 0.0% port· 8K sh· $-89K QoQ· Q1 2026
New
Hedge Fund
$224K· 0.9% of total· 0.0% port· 10K sh· — QoQ· Q4 2024
New
Hedge Fund
$203K· 0.8% of total· 0.0% port· 6K sh· — QoQ· Q4 2025
New
Hedge Fund
$40K· 0.2% of total· 0.0% port· 800 sh· — QoQ· Q1 2026
Added
Hedge Fund
$12K· 0.0% of total· 0.0% port· 245 sh· +$10K QoQ· Q1 2026