TAYSHA GENE THERAPIES INC (TSHA): Ownership & Insider Activity

Hedge funds and institutional managers reporting a position in TSHA · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.

Reported Holders
18
13F filers
Aggregate Value
$145.9M
Across holders
Last Price
$5.97
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity10 increased5 reduced4 exited
Full exits: Point72 Asset Management, L.P., Hudson Bay Capital Management LP, RENAISSANCE TECHNOLOGIES LLC, TUDOR INVESTMENT CORP ET AL
Institutional Holders of TSHA
18 holders
ManagerTypeSharesMarket Value% of Total% of PortfolioActionQoQ ChangeQuarter
SHAW D E & CO INC
CIK 0001009207
Hedge Fund4.40M$30.0M20.5%0.0%Reduced$-21.3MQ2 2026
BAKER BROS. ADVISORS LP
CIK 0001263508
Hedge Fund4.00M$27.3M18.7%0.1%Unchanged+$0Q2 2026
FARALLON CAPITAL MANAGEMENT LLC
CIK 0000909661
Hedge Fund2.25M$15.3M10.5%0.1%AddedQ2 2026
MILLENNIUM MANAGEMENT LLC
CIK 0001273087
Hedge Fund2.13M$14.5M9.9%0.0%Reduced$-7.9MQ2 2026
ORBIMED ADVISORS LLC
CIK 0001055951
Hedge Fund2.00M$13.6M9.3%0.3%AddedQ2 2026
TYBOURNE CAPITAL MANAGEMENT HK LTD
CIK 0001553936
Hedge Fund3.70M$12.1M8.3%39.1%Reduced$-1.3MQ3 2025
CITADEL ADVISORS LLC
CIK 0001423053
Hedge Fund1.54M$10.5M7.2%0.0%Added+$9.8MQ2 2026
Squarepoint Ops LLC
CIK 0001642575
Hedge Fund569K$3.9M2.7%0.0%Added+$1.1MQ2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.
CIK 0001165408
Hedge Fund553K$3.8M2.6%0.0%AddedQ2 2026
Woodline Partners LP
CIK 0001784547
Hedge Fund514K$3.5M2.4%0.0%Unchanged+$0Q2 2026
SHAW D E & CO INCReduced
Hedge Fund
$30.0M· 20.5% of total· 0.0% port· 4.40M sh· $-21.3M QoQ· Q2 2026
BAKER BROS. ADVISORS LPUnchanged
Hedge Fund
$27.3M· 18.7% of total· 0.1% port· 4.00M sh· +$0 QoQ· Q2 2026
FARALLON CAPITAL MANAGEMENT LLCAdded
Hedge Fund
$15.3M· 10.5% of total· 0.1% port· 2.25M sh· QoQ· Q2 2026
MILLENNIUM MANAGEMENT LLCReduced
Hedge Fund
$14.5M· 9.9% of total· 0.0% port· 2.13M sh· $-7.9M QoQ· Q2 2026
ORBIMED ADVISORS LLCAdded
Hedge Fund
$13.6M· 9.3% of total· 0.3% port· 2.00M sh· QoQ· Q2 2026
TYBOURNE CAPITAL MANAGEMENT HK LTDReduced
Hedge Fund
$12.1M· 8.3% of total· 39.1% port· 3.70M sh· $-1.3M QoQ· Q3 2025
CITADEL ADVISORS LLCAdded
Hedge Fund
$10.5M· 7.2% of total· 0.0% port· 1.54M sh· +$9.8M QoQ· Q2 2026
Squarepoint Ops LLCAdded
Hedge Fund
$3.9M· 2.7% of total· 0.0% port· 569K sh· +$1.1M QoQ· Q2 2026
ADAGE CAPITAL PARTNERS GP, L.L.C.Added
Hedge Fund
$3.8M· 2.6% of total· 0.0% port· 553K sh· QoQ· Q2 2026
Woodline Partners LPUnchanged
Hedge Fund
$3.5M· 2.4% of total· 0.0% port· 514K sh· +$0 QoQ· Q2 2026
Holocene Advisors, LPAdded
Hedge Fund
$3.5M· 2.4% of total· 0.0% port· 510K sh· QoQ· Q2 2026
MOORE CAPITAL MANAGEMENT, LPAdded
Hedge Fund
$2.4M· 1.7% of total· 0.0% port· 358K sh· +$201K QoQ· Q2 2026
Qube Research & Technologies LtdAdded
Hedge Fund
$1.8M· 1.2% of total· 0.0% port· 260K sh· QoQ· Q2 2026
TWO SIGMA INVESTMENTS, LPReduced
Hedge Fund
$1.6M· 1.1% of total· 0.0% port· 235K sh· $-3.5M QoQ· Q2 2026
BALYASNY ASSET MANAGEMENT LLCAdded
Hedge Fund
$1.3M· 0.9% of total· 0.0% port· 189K sh· +$724K QoQ· Q2 2026
AQR CAPITAL MANAGEMENT LLCReduced
Hedge Fund
$877K· 0.6% of total· 0.0% port· 129K sh· +$845K QoQ· Q2 2026
Magnetar Financial LLCAdded
Hedge Fund
$78K· 0.1% of total· 0.0% port· 11K sh· +$449 QoQ· Q2 2026
Rockefeller Capital Management L.P.Unchanged
Hedge Fund
$34K· 0.0% of total· 0.0% port· 5K sh· +$0 QoQ· Q2 2026
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