XENON PHARMACEUTICALS INC (XENE): Ownership & Insider Activity
Hedge funds and institutional managers reporting a position in XENE · Health Care. Based on the most recent 13F filing from each holder, sourced from SEC EDGAR.
Reported Holders
27
13F filers
Aggregate Value
$504.7M
Across holders
Last Price
$60.56
2026-08-24
Sector
Health Care
GICS
Quarterly fund activity14 increased10 reduced2 exited
Full exits: Qube Research & Technologies Ltd, Holocene Advisors, LP
| Manager⇅ | Type⇅ | Shares⇅ | Market Value▼ | % of Total⇅ | % of Portfolio⇅ | Action⇅ | QoQ Change⇅ | Quarter⇅ |
|---|---|---|---|---|---|---|---|---|
| TWO SIGMA INVESTMENTS, LP CIK 0001179392 | Hedge Fund | 1.64M | $99.2M | 19.6% | 0.1% | Added | +$62.6M | Q2 2026 |
| CITADEL ADVISORS LLC CIK 0001423053 | Hedge Fund | 1.40M | $84.6M | 16.8% | 0.0% | Reduced | +$68.8M | Q2 2026 |
| ORBIMED ADVISORS LLC CIK 0001055951 | Hedge Fund | 892K | $53.9M | 10.7% | 1.0% | Reduced | $-10.1M | Q2 2026 |
| MARSHALL WACE, LLP CIK 0001318757 | Hedge Fund | 689K | $41.6M | 8.2% | 0.0% | Added | — | Q2 2026 |
| TUDOR INVESTMENT CORP ET AL CIK 0000923093 | Hedge Fund | 545K | $32.9M | 6.5% | 0.0% | Added | +$30.1M | Q2 2026 |
| MILLENNIUM MANAGEMENT LLC CIK 0001273087 | Hedge Fund | 377K | $22.7M | 4.5% | 0.0% | Added | +$10.6M | Q2 2026 |
| BAKER BROS. ADVISORS LP CIK 0001263508 | Hedge Fund | 370K | $22.3M | 4.4% | 0.1% | Unchanged | +$0 | Q2 2026 |
| Man Group plc CIK 0001637460 | Hedge Fund | 311K | $18.7M | 3.7% | 0.0% | Added | — | Q2 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. CIK 0001165408 | Hedge Fund | 300K | $18.1M | 3.6% | 0.0% | Reduced | $-10.3M | Q2 2026 |
| Duquesne Family Office LLC CIK 0001536411 | Family Office | 239K | $14.4M | 2.9% | 0.3% | Unchanged | +$0 | Q2 2026 |
Added
Hedge Fund
$99.2M· 19.6% of total· 0.1% port· 1.64M sh· +$62.6M QoQ· Q2 2026
Reduced
Hedge Fund
$84.6M· 16.8% of total· 0.0% port· 1.40M sh· +$68.8M QoQ· Q2 2026
Reduced
Hedge Fund
$53.9M· 10.7% of total· 1.0% port· 892K sh· $-10.1M QoQ· Q2 2026
Added
Hedge Fund
$41.6M· 8.2% of total· 0.0% port· 689K sh· — QoQ· Q2 2026
Added
Hedge Fund
$32.9M· 6.5% of total· 0.0% port· 545K sh· +$30.1M QoQ· Q2 2026
Added
Hedge Fund
$22.7M· 4.5% of total· 0.0% port· 377K sh· +$10.6M QoQ· Q2 2026
Unchanged
Hedge Fund
$22.3M· 4.4% of total· 0.1% port· 370K sh· +$0 QoQ· Q2 2026
Added
Hedge Fund
$18.7M· 3.7% of total· 0.0% port· 311K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$18.1M· 3.6% of total· 0.0% port· 300K sh· $-10.3M QoQ· Q2 2026
Unchanged
Family Office
$14.4M· 2.9% of total· 0.3% port· 239K sh· +$0 QoQ· Q2 2026
Reduced
Hedge Fund
$13.7M· 2.7% of total· 0.0% port· 227K sh· $-5.9M QoQ· Q2 2026
Added
Hedge Fund
$13.5M· 2.7% of total· 0.0% port· 224K sh· +$12.4M QoQ· Q2 2026
Reduced
Hedge Fund
$11.7M· 2.3% of total· 0.0% port· 193K sh· +$11.6M QoQ· Q2 2026
Reduced
Hedge Fund
$11.3M· 2.2% of total· 0.0% port· 187K sh· $-6.8M QoQ· Q2 2026
Added
Hedge Fund
$9.4M· 1.9% of total· 0.0% port· 155K sh· +$302K QoQ· Q2 2026
Added
Hedge Fund
$7.9M· 1.6% of total· 0.0% port· 130K sh· +$7.3M QoQ· Q2 2026
Added
Hedge Fund
$6.8M· 1.3% of total· 0.0% port· 113K sh· — QoQ· Q2 2026
Added
Hedge Fund
$6.5M· 1.3% of total· 0.1% port· 108K sh· +$523K QoQ· Q2 2026
Added
Hedge Fund
$5.1M· 1.0% of total· 0.0% port· 85K sh· — QoQ· Q2 2026
Added
Hedge Fund
$4.6M· 0.9% of total· 0.0% port· 77K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$2.4M· 0.5% of total· 0.0% port· 40K sh· $-905K QoQ· Q2 2026
Added
Hedge Fund
$1.1M· 0.2% of total· 0.0% port· 18K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$600K· 0.1% of total· 0.0% port· 10K sh· +$115K QoQ· Q2 2026
Added
Hedge Fund
$539K· 0.1% of total· 0.0% port· 9K sh· — QoQ· Q2 2026
Reduced
Hedge Fund
$529K· 0.1% of total· 0.0% port· 9K sh· +$210K QoQ· Q2 2026
Reduced
Hedge Fund
$438K· 0.1% of total· 0.0% port· 7K sh· $-2.2M QoQ· Q2 2026
Unchanged
Hedge Fund
$12K· 0.0% of total· 0.0% port· 200 sh· +$0 QoQ· Q2 2026
1–10 of 27
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